What do we want?
To diagnose cancer a piece of tissue is taken from the affected area. This can be
part of the normal treatment like removal ofthe cancer mass by means of
operation or a tissue biopsy can be taken for diagnostic reasons. This is tissue is
routinely send to a pathology department to precisely diagnose the cancer.
Usually only a small sample of the tissue biopsy is needed for the diagnosis. Just
as written information is stored in patients' notes the sample used to diagnose
cancer is then kept in the archives of the pathology department. These archives
can also be used for medical research.
The parts of the tissue, which are not used for diagnosis, are residual tissues.
These are later when the diagnosis is complete destroyed. This is the tissue,
which cancer researchers want to collect for medical research purposes. The
best way to preserve the tissues is to snap freeze small samples and store these
in liquid nitrogen for future use.
The preserved tissue of a cancer contains clues about how cancer develops.
We want to collect and store this valuable tissue in order for it to be used in future
However, one comprehensive cancer center is often not able to collect enough
samples of a certain type or subtype of cancer to do the required statistical
significant experiments to be absolutely sure the results are right.
Therefore, OECI-TuBaFrost wants to enable cancer researchers to find large
amounts of high quality samples needed to do the needed statistical significant
experiments. These can be shared amongst the participating institutes and/or
amongst consortia in a project-supporting environment. In addition, offer a
complete exchange platform with rules for access, exchange, standardization,
harmonization,annotation and use, so exchange is in line with local law and
ethics and with high quality samples and data.
What will happen with the tissue ?
There are strict instructions about how to store human tissue. These are
individual to each country. All tissue will be frozen in an internationally
standardized way. The frozen tissue will then be stored in the hospital where the
patient has been diagnosed/treated.
All of the tissue samples for the collection are given a code number. This is so all
samples are anonymous. This is usually done by the technician who works
closely with the pathologist involved in the diagnosis of the original tissue
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